Injecting minute amounts of two immune-stimulating agents directly into solid tumors in mice was able to eliminate all traces of cancer in the animals — including distant, untreated metastases (spreading cancer locations), according to a study by Stanford University School of Medicine researchers.
The researchers believe this new “in situ vaccination” method could serve as a rapid and relatively inexpensive cancer therapy — one that is unlikely to cause the adverse side effects often seen with bodywide immune stimulation.
The  approach works for many different types of cancers, including those that arise spontaneously, the study found.
“When we use these two agents together, we see the elimination of tumors all over the body,” said Ronald Levy*, MD, professor of oncology and senior author of the study, which was published Jan. 31 in Science Translational Medicine. “This approach bypasses the need to identify tumor-specific immune targets and doesn’t require wholesale activation of the immune system or …
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